Supplement manufacturers in the USA
EPA records list 832 active supplement makers in the US, facilities with codes for vitamins, supplements and botanical products (medicinal and botanical manufacturing). The most are in California, New Jersey and Colorado, with 49% of the total.
- Product
- Supplement manufacturers
- Facilities
- 832
- States
- 45
- NAICS
- 325411
- Revised
- November 1, 2026
By state
States with at least 15 such facilities have their own page with the facility list.
| State | Facilities | Share |
|---|---|---|
| California | 310 | 37.3% |
| New Jersey | 57 | 6.9% |
| Colorado | 42 | 5.0% |
| Missouri | 35 | 4.2% |
| Massachusetts | 30 | 3.6% |
| Illinois | 27 | 3.2% |
| New York | 26 | 3.1% |
| Pennsylvania | 26 | 3.1% |
| Michigan | 24 | 2.9% |
| Texas | 21 | 2.5% |
| Florida | 20 | 2.4% |
| North Carolina | 19 | 2.3% |
| South Carolina | 19 | 2.3% |
| Indiana | 16 | 1.9% |
| Oregon | 15 | 1.8% |
| Washington | 12 | 1.4% |
| Iowa | 11 | 1.3% |
| Nevada | 10 | 1.2% |
| Wisconsin | 10 | 1.2% |
| Maryland | 9 | 1.1% |
| Utah | 8 | 1.0% |
| Virginia | 8 | 1.0% |
| Georgia | 7 | 0.8% |
| Ohio | 7 | 0.8% |
| Arizona | 6 | 0.7% |
| Connecticut | 6 | 0.7% |
| Tennessee | 6 | 0.7% |
| West Virginia | 5 | 0.6% |
| Arkansas | 4 | 0.5% |
| Nebraska | 4 | 0.5% |
| New Hampshire | 4 | 0.5% |
| Delaware | 3 | 0.4% |
| Kansas | 3 | 0.4% |
| Kentucky | 3 | 0.4% |
| Mississippi | 3 | 0.4% |
| Rhode Island | 3 | 0.4% |
| Alabama | 2 | 0.2% |
| Idaho | 2 | 0.2% |
| Minnesota | 2 | 0.2% |
| New Mexico | 2 | 0.2% |
| Louisiana | 1 | 0.1% |
| Maine | 1 | 0.1% |
| Montana | 1 | 0.1% |
| Oklahoma | 1 | 0.1% |
| Vermont | 1 | 0.1% |
EPA ECHO active facilities listing NAICS 325411. Codes are reported by facilities and not checked here. How these records work.
Biggest clusters
- Los Angeles, CA: 23
- San Diego, CA: 16
- Oakland, CA: 11
- Santa Rosa, CA: 11
- Sacramento, CA: 9
- Desert Hot Springs, CA: 9
- Boulder, CO: 7
- Loveland, CO: 5
Codes counted
- Medicinal and Botanical Manufacturing (NAICS 325411)
This sits inside chemicals manufacturing, which has 14,543 establishments and 911,245 jobs (Census, 2023). See the industry.