Chemicals manufacturers in South Dakota
South Dakota has 39 chemicals establishments employing 1,415 people (Census, 2023), and EPA's ECHO database lists 39 active chemicals facilities in the state. By employment it is South Dakota's number 13 manufacturing industry, and South Dakota ranks number 46 among states for it.
- NAICS subsector
- 325
- Chemical Manufacturing
- Establishments
- 39
- Census 2023
- Employees
- 1,415
- Census 2023
- In EPA records
- 39
- With a page here
- 7
- Revised
- November 11, 2026
Chemicals factories with a page
| Facility | What it makes (NAICS) | City |
|---|---|---|
| Glacial Lakes Energy LLC | Ethyl Alcohol Manufacturing | Watertown |
| Nugen Energy LLC | Ethyl Alcohol Manufacturing | Marion |
| Poet Biorefining - Groton | Ethyl Alcohol Manufacturing | Groton |
| Poet Biorefining - Hudson | Ethyl Alcohol Manufacturing | Hudson |
| Poet Biorefining Mitchell, LLC | Ethyl Alcohol Manufacturing | Mitchell |
| Poet Biorefining-Chancellor | Ethyl Alcohol Manufacturing | Chancellor |
| Poet Research Center | Ethyl Alcohol Manufacturing | Scotland |
These are the South Dakota chemicals facilities that report to EPA's Toxics Release Inventory. The other 32 in EPA records don't have a page yet.
What these factories make
- Ethyl Alcohol Manufacturing (NAICS 325193): 7 facilities
- Petrochemical Manufacturing (NAICS 325110): 6 facilities
- All Other Basic Organic Chemical Manufacturing (NAICS 325199): 1 facility
Where they cluster
Cities with the most active chemicals facilities in EPA records: Brandon (3), Mitchell (3), Aberdeen (2), Mina (2), Watertown (2).
Chemicals manufacturing across the US. Everything made in South Dakota.