Amgen North Carolina drug substance facility
Amgen, Holly Springs, Wake County, North Carolina
Amgen North Carolina drug substance facility in Holly Springs, North Carolina is Amgen’s plant for biologic drug substance. Status: operating as of January 24, 2025 (opened). Amgen announced $550 million and 355 jobs. Primary source: commerce.nc.gov, checked November 1, 2026.
- Status
- Operating
- Announced investment
- $550 million
- Announced jobs
- 355
- Industry
- Pharmaceuticals
- Sheet
- NC-02
- Revised
- November 1, 2026
Status timeline
- Announcedcommerce.nc.gov
- Groundbreakingamgen.com
- Openedamgen.com
Filled dots are confirmed by a company, state, SEC or federal source. Dashed dots come from news reports only. Investment and job figures are as announced, not achieved.
Plant facts
| Company | Amgen |
|---|---|
| Plant | Amgen North Carolina drug substance facility |
| Location | Holly Springs, Wake County, North Carolina |
| Industry | Pharmaceuticals |
| Product | Biologic drug substance |
| Announced investment | $550 millionInitial facility per 2021 state release; Amgen later added a $1B expansion (combined ~$1.5B) |
| Announced jobs | 355 |
| Last checked | November 1, 2026 |
Sources
- Gov. Cooper: Amgen to create 355 jobs (state release, commerce.nc.gov, checked November 1, 2026)
- Amgen breaks ground in North Carolina (company release, amgen.com, checked November 1, 2026)
- Amgen NC ribbon cutting (company release, amgen.com, checked November 1, 2026)
- ABC11: Amgen opens Holly Springs campus (news report, abc11.com, checked November 1, 2026)
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